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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50159202
(N-[3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol...)
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Affinity Data
Ki: 1nM
Assay Description:
Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50044624
(CHEMBL606765)
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Affinity Data
Ki: 12nM
Assay Description:
Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50159202
(N-[3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 12nM
Assay Description:
Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50159202
(N-[3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 14.1nM
Assay Description:
Inhibition of 5-HT stimulated cAMP production in HeLa cells expressing human 5-hydroxytryptamine 6 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50159202
(N-[3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.20nM
Assay Description:
Effective agonist concentration in cAMP release assay in HeLa cells expressing human 5-hydroxytryptamine 6 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI