Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
D(1A) dopamine receptor
(RAT)
Vanderbilt University
Curated by
ChEMBL
Ligand
BDBM50010592
(1-(8-Chloro-5-methylene-5H-dibenzo[a,d]cyclohepten...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8nM
Assay Description:
Binding affinity against Dopamine receptor D1 using [3H]-SCN 23390 in rat brain
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(RAT)
Vanderbilt University
Curated by
ChEMBL
Ligand
BDBM50010592
(1-(8-Chloro-5-methylene-5H-dibenzo[a,d]cyclohepten...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 21nM
Assay Description:
Binding activity against Dopamine receptor D1 in rat brain, using [3H]-SCH-23,390 as the radioligand
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Vanderbilt University
Curated by
ChEMBL
Ligand
BDBM50010592
(1-(8-Chloro-5-methylene-5H-dibenzo[a,d]cyclohepten...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 27nM
Assay Description:
Binding affinity for Dopamine receptor D2 using [3H]-spiperone in rat brain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5
(RAT)
Vanderbilt University
Curated by
ChEMBL
Ligand
BDBM50010592
(1-(8-Chloro-5-methylene-5H-dibenzo[a,d]cyclohepten...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 150nM
Assay Description:
Binding activity against muscarinic acetylcholine receptor in rat brain using [3H]QNB as the radioligand
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Vanderbilt University
Curated by
ChEMBL
Ligand
BDBM50010592
(1-(8-Chloro-5-methylene-5H-dibenzo[a,d]cyclohepten...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 305nM
Assay Description:
Binding activity against dopamine receptor D2 in rat brain, using [3H]-Spiperone as the radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5
(RAT)
Vanderbilt University
Curated by
ChEMBL
Ligand
BDBM50010592
(1-(8-Chloro-5-methylene-5H-dibenzo[a,d]cyclohepten...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 330nM
Assay Description:
Binding affinity was determined against Muscarinic acetylcholine receptor using [3H]QNB as radioligand in rat brain.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI