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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
Vanderbilt University
Curated by
ChEMBL
Ligand
BDBM50028979
(8-Chloro-5-methyl-11-(4-methyl-piperazin-1-yl)-5H-...)
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Affinity Data
Ki: 40nM
Assay Description:
Affinity of the compound was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 3 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
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Article
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Rattus norvegicus (Rat))
Vanderbilt University
Curated by
ChEMBL
Ligand
BDBM50028979
(8-Chloro-5-methyl-11-(4-methyl-piperazin-1-yl)-5H-...)
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Affinity Data
Ki: 74nM
Assay Description:
Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 2C receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
D(4) dopamine receptor
(Homo sapiens (Human))
Vanderbilt University
Curated by
ChEMBL
Ligand
BDBM50028979
(8-Chloro-5-methyl-11-(4-methyl-piperazin-1-yl)-5H-...)
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Affinity Data
Ki: 120nM
Assay Description:
Affinity was evaluated as inhibition constant for dopamine D-4 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Vanderbilt University
Curated by
ChEMBL
Ligand
BDBM50028979
(8-Chloro-5-methyl-11-(4-methyl-piperazin-1-yl)-5H-...)
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Copy InChI
Affinity Data
Ki: 140nM
Assay Description:
Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 2A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
D(2) dopamine receptor
(Homo sapiens (Human))
Vanderbilt University
Curated by
ChEMBL
Ligand
BDBM50028979
(8-Chloro-5-methyl-11-(4-methyl-piperazin-1-yl)-5H-...)
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Affinity Data
Ki: 1.10E+3nM
Assay Description:
Affinity was evaluated as inhibition constant for dopamine D-2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50028979
(8-Chloro-5-methyl-11-(4-methyl-piperazin-1-yl)-5H-...)
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Affinity Data
IC50: 12nM
Assay Description:
Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50028979
(8-Chloro-5-methyl-11-(4-methyl-piperazin-1-yl)-5H-...)
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Affinity Data
IC50: 3.24E+4nM
Assay Description:
Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nuclei
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI