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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028979(8-Chloro-5-methyl-11-(4-methyl-piperazin-1-yl)-5H-...)
Affinity DataKi:  40nMAssay Description:Affinity of the compound was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028979(8-Chloro-5-methyl-11-(4-methyl-piperazin-1-yl)-5H-...)
Affinity DataKi:  74nMAssay Description:Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028979(8-Chloro-5-methyl-11-(4-methyl-piperazin-1-yl)-5H-...)
Affinity DataKi:  120nMAssay Description:Affinity was evaluated as inhibition constant for dopamine D-4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028979(8-Chloro-5-methyl-11-(4-methyl-piperazin-1-yl)-5H-...)
Affinity DataKi:  140nMAssay Description:Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028979(8-Chloro-5-methyl-11-(4-methyl-piperazin-1-yl)-5H-...)
Affinity DataKi:  1.10E+3nMAssay Description:Affinity was evaluated as inhibition constant for dopamine D-2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50028979(8-Chloro-5-methyl-11-(4-methyl-piperazin-1-yl)-5H-...)
Affinity DataIC50:  12nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50028979(8-Chloro-5-methyl-11-(4-methyl-piperazin-1-yl)-5H-...)
Affinity DataIC50:  3.24E+4nMAssay Description:Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nucleiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed