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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human))
University Of GöTeborg
Curated by
ChEMBL
Ligand
BDBM50078065
(CHEMBL70609 | Methanesulfonic acid 11-(4-methyl-pi...)
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Affinity Data
IC50: 38nM
Assay Description:
Inhibition of binding of 1.0 nM [3H]-pirenzepine to cloned human Muscarinic acetylcholine receptor M1 expressed in membranes from CHO-K1 cells
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
University Of GöTeborg
Curated by
ChEMBL
Ligand
BDBM50078065
(CHEMBL70609 | Methanesulfonic acid 11-(4-methyl-pi...)
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Affinity Data
IC50: 4.90E+3nM
Assay Description:
Binding affinity towards 5-hydroxytryptamine 2A receptor from rat frontal cortex using [3H]-ketanserin as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Rattus norvegicus (Rat))
University Of GöTeborg
Curated by
ChEMBL
Ligand
BDBM50078065
(CHEMBL70609 | Methanesulfonic acid 11-(4-methyl-pi...)
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Affinity Data
IC50: 7.40E+3nM
Assay Description:
Binding affinity towards 5-HT2C receptor from rat using [3H]-mesulergine as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
D(1A) dopamine receptor
(RAT)
University Of GöTeborg
Curated by
ChEMBL
Ligand
BDBM50078065
(CHEMBL70609 | Methanesulfonic acid 11-(4-methyl-pi...)
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Affinity Data
IC50: 2.20E+4nM
Assay Description:
Binding affinity towards D1 CNS receptor of rat corpus striatum using [3H]-SCH-23,390 as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University Of GöTeborg
Curated by
ChEMBL
Ligand
BDBM50078065
(CHEMBL70609 | Methanesulfonic acid 11-(4-methyl-pi...)
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Affinity Data
IC50: 3.30E+4nM
Assay Description:
Binding affinity towards Dopamine receptor D2 of rat corpus striatum using [3H]-spiperone as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI