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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Amgen
Ligand
BDBM26381
(1-N-[3-fluoro-5-(trifluoromethyl)benzene]-4-methyl...)
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Affinity Data
IC50: 0.300nM
pH: 7.5 T: 2°C
Assay Description:
The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Amgen
Ligand
BDBM26381
(1-N-[3-fluoro-5-(trifluoromethyl)benzene]-4-methyl...)
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Affinity Data
IC50: 3nM
Assay Description:
In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Amgen
Ligand
BDBM26381
(1-N-[3-fluoro-5-(trifluoromethyl)benzene]-4-methyl...)
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Affinity Data
IC50: 17nM
Assay Description:
The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Angiopoietin-1 receptor
(Homo sapiens (Human))
Amgen
Ligand
BDBM26381
(1-N-[3-fluoro-5-(trifluoromethyl)benzene]-4-methyl...)
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Affinity Data
IC50: 6.08E+3nM
Assay Description:
The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase JAK3
(Homo sapiens (Human))
Amgen
Ligand
BDBM26381
(1-N-[3-fluoro-5-(trifluoromethyl)benzene]-4-methyl...)
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Copy InChI
Affinity Data
IC50: >2.50E+4nM
Assay Description:
The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI