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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Aurora kinase A
(Homo sapiens (Human))
Nerviano Medical Sciences
Ligand
BDBM12983
(5-Amido-pyrrolopyrazole 9b | CHEMBL385872 | N-{5-[...)
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Affinity Data
IC50: 6nM
pH: 7.5 T: 2°C
Assay Description:
The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase A
(Homo sapiens (Human))
Nerviano Medical Sciences
Ligand
BDBM12983
(5-Amido-pyrrolopyrazole 9b | CHEMBL385872 | N-{5-[...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6nM
Assay Description:
Inhibition of aurora A kinase
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase B
(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM12983
(5-Amido-pyrrolopyrazole 9b | CHEMBL385872 | N-{5-[...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 48nM
Assay Description:
Inhibition of aurora B kinase
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase B
(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM12983
(5-Amido-pyrrolopyrazole 9b | CHEMBL385872 | N-{5-[...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 48nM
pH: 7.5 T: 2°C
Assay Description:
The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI