Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239027(US10028934, Compound 35 | US10478423, Cpd. 35 | US...)
Affinity DataIC50:  1.18E+3nMAssay Description:i. Enzyme—The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239027(US10028934, Compound 35 | US10478423, Cpd. 35 | US...)
Affinity DataIC50:  1.18E+3nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239027(US10028934, Compound 35 | US10478423, Cpd. 35 | US...)
Affinity DataIC50:  1.18E+3nMAssay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3 [564-993](Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239027(US10028934, Compound 35 | US10478423, Cpd. 35 | US...)
Affinity DataIC50:  1.18E+3nMpH: 7.9 T: 2°CAssay Description:The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was pre activat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239027(US10028934, Compound 35 | US10478423, Cpd. 35 | US...)
Affinity DataIC50:  2.37E+3nMAssay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239027(US10028934, Compound 35 | US10478423, Cpd. 35 | US...)
Affinity DataIC50:  2.37E+3nMAssay Description:i. Enzyme—The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit [544-976](Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239027(US10028934, Compound 35 | US10478423, Cpd. 35 | US...)
Affinity DataIC50:  2.37E+3nMpH: 7.9Assay Description:The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) was pre ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239027(US10028934, Compound 35 | US10478423, Cpd. 35 | US...)
Affinity DataIC50:  2.37E+3nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent