Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50203571(1-(7-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)met...)Copy SMILESCopy InChI

Affinity DataKi: <1nMAssay Description:Displacement of [3H]5-hydroxytrytamine from human 5HT1B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatents

In DepthDetails ArticlePubMed
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TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50203571(1-(7-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)met...)Copy SMILESCopy InChI

Affinity DataKi:  500nMAssay Description:Displacement of [3H]NPTS from human GlyT1C expressed in HEK293 cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50203571(1-(7-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)met...)Copy SMILESCopy InChI

Affinity DataKi:  1.28E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI