Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM66782(1-(4-chlorophenyl)-3-[2-(4-methyl-1-piperazinyl)et...)
Affinity DataIC50:  1.59E+3nMAssay Description:Allosteric antagonist activity at human CB1 receptor expressed in CHO-RD-HGA16 cells overexpressing Galpha16 assessed as inhibition of CP55940-stimul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM66782(1-(4-chlorophenyl)-3-[2-(4-methyl-1-piperazinyl)et...)
Affinity DataIC50:  7.94E+3nMAssay Description:Allosteric antagonist activity at human CB1 receptor expressed in HEK293 cell membrane assessed as inhibition of CP55940-stimulated [35S]GTPgammaS bi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM66782(1-(4-chlorophenyl)-3-[2-(4-methyl-1-piperazinyl)et...)
Affinity DataIC50: <1.00E+4nMAssay Description:Antagonist activity at human CB2 receptor expressed in CHO-RD-HGA16 cells overexpressing Galpha16 assessed as inhibition of CP55940-stimulated calciu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 11(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM66782(1-(4-chlorophenyl)-3-[2-(4-methyl-1-piperazinyl)et...)
Affinity DataEC50: >3.50E+5nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay