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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Cannabinoid receptor 1
(Homo sapiens (Human))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM66782
(1-(4-chlorophenyl)-3-[2-(4-methyl-1-piperazinyl)et...)
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Affinity Data
IC50: 1.59E+3nM
Assay Description:
Allosteric antagonist activity at human CB1 receptor expressed in CHO-RD-HGA16 cells overexpressing Galpha16 assessed as inhibition of CP55940-stimul...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cannabinoid receptor 1
(Homo sapiens (Human))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM66782
(1-(4-chlorophenyl)-3-[2-(4-methyl-1-piperazinyl)et...)
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Copy InChI
Affinity Data
IC50: 7.94E+3nM
Assay Description:
Allosteric antagonist activity at human CB1 receptor expressed in HEK293 cell membrane assessed as inhibition of CP55940-stimulated [35S]GTPgammaS bi...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cannabinoid receptor 2
(Homo sapiens (Human))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM66782
(1-(4-chlorophenyl)-3-[2-(4-methyl-1-piperazinyl)et...)
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Affinity Data
IC50: <1.00E+4nM
Assay Description:
Antagonist activity at human CB2 receptor expressed in CHO-RD-HGA16 cells overexpressing Galpha16 assessed as inhibition of CP55940-stimulated calciu...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bcl-2-like protein 11
(Homo sapiens (Human))
Broad Institute
Curated by
PubChem BioAssay
Ligand
BDBM66782
(1-(4-chlorophenyl)-3-[2-(4-methyl-1-piperazinyl)et...)
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Affinity Data
EC50: >3.50E+5nM
Assay Description:
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI