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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
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Target
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical
Ligand
BDBM27890
(8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(4-methylpi...)
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Affinity Data
IC50: 0.800nM
pH: 7.5 T: 2°C
Assay Description:
FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...
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Target Info
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical
Ligand
BDBM27890
(8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(4-methylpi...)
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Affinity Data
IC50: 1nM
T: 2°C
Assay Description:
FLT-3 was assayed using a fluorescence polarization (FP) competition immunoassay that measured FLT-3 phosphorylation of polyGlu4Tyr. The reaction was...
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Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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Article
PubMed
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Target
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical
Ligand
BDBM27890
(8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(4-methylpi...)
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Affinity Data
IC50: 8nM
Assay Description:
Inhibition of ATP-induced CSF1R autophosphorylation
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Target Info
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UniProtKB/SwissProt
antibodypedia
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PC sid
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In Depth
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Article
PubMed
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical
Ligand
BDBM27890
(8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(4-methylpi...)
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Affinity Data
IC50: 20nM
T: 2°C
Assay Description:
KIT was assayed using a fluorescence polarization (FP) competition immunoassay that measured KIT phosphorylation of polyGlu4Tyr. The reaction was ini...
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Target
High affinity nerve growth factor receptor [440-796]
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical
Ligand
BDBM27890
(8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(4-methylpi...)
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Affinity Data
IC50: 170nM
T: 2°C
Assay Description:
TrkA was assayed using a fluorescence polarization (FP) competition immunoassay that measured TrkA phosphorylation of polyGlu4Tyr. The reaction was i...
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KEGG
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Target
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical
Ligand
BDBM27890
(8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(4-methylpi...)
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Affinity Data
IC50: >500nM
T: 2°C
Assay Description:
Axl was assayed using a fluorescence polarization (FP) competition immunoassay that measured Axl phosphorylation of polyGlu4Tyr. The reaction was ini...
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Target Info
PDB
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KEGG
UniProtKB/SwissProt
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antibodypedia
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Article
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Target
Insulin receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical
Ligand
BDBM27890
(8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(4-methylpi...)
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Affinity Data
IC50: >4.20E+4nM
T: 2°C
Assay Description:
IRKbeta was assayed using a fluorescence polarization (FP) competition immunoassay that measured IRKbeta phosphorylation of polyGlu4Tyr. The reaction...
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Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
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antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
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In Depth
Details
Article
PubMed
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