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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50264990
(CHEMBL496129 | N-(4'-(2-aminothiazol-4-yl)-6-methy...)
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Affinity Data
Ki: >850nM
Assay Description:
Displacement of fluorescent ATP competitive ligand from p38alpha
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50264990
(CHEMBL496129 | N-(4'-(2-aminothiazol-4-yl)-6-methy...)
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Affinity Data
IC50: 90nM
Assay Description:
Inhibition of cFMS
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50264990
(CHEMBL496129 | N-(4'-(2-aminothiazol-4-yl)-6-methy...)
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Affinity Data
IC50: 2.00E+3nM
Assay Description:
Inhibition of LCK
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Mitogen-activated protein kinase 10
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50264990
(CHEMBL496129 | N-(4'-(2-aminothiazol-4-yl)-6-methy...)
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Affinity Data
IC50: >1.60E+4nM
Assay Description:
Inhibition of JNK3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Cyclin-dependent kinase 2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50264990
(CHEMBL496129 | N-(4'-(2-aminothiazol-4-yl)-6-methy...)
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Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of CDK2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50264990
(CHEMBL496129 | N-(4'-(2-aminothiazol-4-yl)-6-methy...)
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Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of VEGFR2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50264990
(CHEMBL496129 | N-(4'-(2-aminothiazol-4-yl)-6-methy...)
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Affinity Data
IC50: >2.50E+4nM
Assay Description:
Inhibition of PLK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50264990
(CHEMBL496129 | N-(4'-(2-aminothiazol-4-yl)-6-methy...)
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Affinity Data
IC50: >2.50E+4nM
Assay Description:
Inhibition of EGFR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-4
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50264990
(CHEMBL496129 | N-(4'-(2-aminothiazol-4-yl)-6-methy...)
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Affinity Data
IC50: >2.50E+4nM
Assay Description:
Inhibition of ErbB4
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Sgk1
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50264990
(CHEMBL496129 | N-(4'-(2-aminothiazol-4-yl)-6-methy...)
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Affinity Data
IC50: >3.30E+4nM
Assay Description:
Inhibition of SGK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI