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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50157314
((S)-4-Methyl-piperazine-2-carboxylic acid [(R)-2-(...)
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Affinity Data
IC50: 7nM
Assay Description:
Concentration for 50% inhibition of human melanocortin-4 receptor expressed in CHO cells using [125I]NDP-alpha-MSH as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50157314
((S)-4-Methyl-piperazine-2-carboxylic acid [(R)-2-(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7nM
Assay Description:
Concentration for 50% inhibition of human melanocortin-4 receptor expressed in CHO cells using [125I]NDP-alpha-MSH as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50157314
((S)-4-Methyl-piperazine-2-carboxylic acid [(R)-2-(...)
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Copy InChI
Affinity Data
IC50: 1.70E+3nM
Assay Description:
Concentration for 50% inhibition of human melanocortin-1 receptor expressed in CHO cells using [125I]-NDP-alpha-MSH as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50157314
((S)-4-Methyl-piperazine-2-carboxylic acid [(R)-2-(...)
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Copy InChI
Affinity Data
IC50: 2.30E+3nM
Assay Description:
Concentration for 50% inhibition of human melanocortin-3 receptor expressed in CHO cells using [125I]NDP-alpha-MSH as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 5
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50157314
((S)-4-Methyl-piperazine-2-carboxylic acid [(R)-2-(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.40E+3nM
Assay Description:
Concentration for 50% inhibition of human melanocortin-5 receptor expressed in CHO cells using [125I]NDP-alpha-MSH as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 5
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50157314
((S)-4-Methyl-piperazine-2-carboxylic acid [(R)-2-(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.40E+3nM
Assay Description:
Concentration for 50% inhibition of human melanocortin-5 receptor expressed in CHO cells using [125I]NDP-alpha-MSH as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50157314
((S)-4-Methyl-piperazine-2-carboxylic acid [(R)-2-(...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 350nM
Assay Description:
Effective concentration towards human melanocortin-1 receptor mediated cAMP accumulation in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50157314
((S)-4-Methyl-piperazine-2-carboxylic acid [(R)-2-(...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 11nM
Assay Description:
Effective concentration towards human melanocortin-4 receptor mediated cAMP accumulation in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 5
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50157314
((S)-4-Methyl-piperazine-2-carboxylic acid [(R)-2-(...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.90E+3nM
Assay Description:
Effective concentration towards human melanocortin-5 receptor mediated cAMP accumulation in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50157314
((S)-4-Methyl-piperazine-2-carboxylic acid [(R)-2-(...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 990nM
Assay Description:
Effective concentration towards human melanocortin-3 receptor mediated cAMP accumulation in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI