Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Abbott

Curated by ChEMBL

LigandBDBM50175484(3-[2-(4-isoquinolin-8-yl-piperazin-1-yl)-ethyl]-7-...)Copy SMILESCopy InChI

Affinity DataKi:  0.100nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Abbott

Curated by ChEMBL

LigandBDBM50175484(3-[2-(4-isoquinolin-8-yl-piperazin-1-yl)-ethyl]-7-...)Copy SMILESCopy InChI

Affinity DataKi:  0.300nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI