Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 17 hits in this display
BDBM50193032(CHEMBL3979343 | US11155556, No. 2)
IC50: 1.5nMAssay Description:Inhibition of human PI3Kdelta (R108 to Q1044 residues) expressed in mammalian expression system incubated for 60 mins by ADAPTA assayMore data for this Ligand-Target Pair
BDBM50193032(CHEMBL3979343 | US11155556, No. 2)
BDBM50193032(CHEMBL3979343 | US11155556, No. 2)
IC50: 2.80nMAssay Description:Inhibition of human PI3Kgamma (S144 to A1102 residues) expressed in mammalian expression system incubated for 60 mins by ADAPTA assayMore data for this Ligand-Target Pair
BDBM50193032(CHEMBL3979343 | US11155556, No. 2)
IC50: 3nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
BDBM50193032(CHEMBL3979343 | US11155556, No. 2)
IC50: 16nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
BDBM50193032(CHEMBL3979343 | US11155556, No. 2)
IC50: 23nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
BDBM50193032(CHEMBL3979343 | US11155556, No. 2)
IC50: 53nMAssay Description:Inhibition of human PI3Kalpha (R108 to N1068 residues) expressed in mammalian expression system incubated for 60 mins by ADAPTA assayMore data for this Ligand-Target Pair
BDBM50193032(CHEMBL3979343 | US11155556, No. 2)
IC50: 53nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
BDBM50193032(CHEMBL3979343 | US11155556, No. 2)
IC50: 59nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
BDBM50193032(CHEMBL3979343 | US11155556, No. 2)
BDBM50193032(CHEMBL3979343 | US11155556, No. 2)
IC50: 112nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
BDBM50193032(CHEMBL3979343 | US11155556, No. 2)
BDBM50193032(CHEMBL3979343 | US11155556, No. 2)
IC50: 120nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
BDBM50193032(CHEMBL3979343 | US11155556, No. 2)
IC50: 231nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
BDBM50193032(CHEMBL3979343 | US11155556, No. 2)
IC50: 540nMAssay Description:Inhibition of human PI3Kbeta (P118 to S1070 residues) expressed in mammalian expression system incubated for 60 mins by ADAPTA assayMore data for this Ligand-Target Pair
BDBM50193032(CHEMBL3979343 | US11155556, No. 2)
IC50: 544nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
BDBM50193032(CHEMBL3979343 | US11155556, No. 2)