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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50082980
((2R,3S)-2-(Benzenesulfonyl-methyl-amino)-N*4*-((S)...)
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Affinity Data
IC50: 0.610nM
Assay Description:
Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Interstitial collagenase
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50082980
((2R,3S)-2-(Benzenesulfonyl-methyl-amino)-N*4*-((S)...)
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Copy InChI
Affinity Data
IC50: 1.5nM
Assay Description:
Inhibitory activity against MMP-1 (Matrix metalloproteinase-1)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50082980
((2R,3S)-2-(Benzenesulfonyl-methyl-amino)-N*4*-((S)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.00E+3nM
Assay Description:
Inhibition of TNF(tumor necrosis factor) in human blood
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI