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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50106027((7S,8R,11S)-8-[3-(3,4-dimethoxy-phenyl)-propyl]-9-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of TACE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50106027((7S,8R,11S)-8-[3-(3,4-dimethoxy-phenyl)-propyl]-9-...)
Affinity DataIC50:  5.01nMAssay Description:Inhibition of TACE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50106027((7S,8R,11S)-8-[3-(3,4-dimethoxy-phenyl)-propyl]-9-...)
Affinity DataIC50:  5.20nMAssay Description:Inhibitory concentration against Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50106027((7S,8R,11S)-8-[3-(3,4-dimethoxy-phenyl)-propyl]-9-...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of TACE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50106027((7S,8R,11S)-8-[3-(3,4-dimethoxy-phenyl)-propyl]-9-...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50106027((7S,8R,11S)-8-[3-(3,4-dimethoxy-phenyl)-propyl]-9-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50106027((7S,8R,11S)-8-[3-(3,4-dimethoxy-phenyl)-propyl]-9-...)
Affinity DataIC50:  180nMAssay Description:Inhibition of TACE (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50106027((7S,8R,11S)-8-[3-(3,4-dimethoxy-phenyl)-propyl]-9-...)
Affinity DataIC50:  180nMAssay Description:Concentration required to inhibit the release of tumor necrosis factor -alpha (TNF-alpha) in THP-1 cellular assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50106027((7S,8R,11S)-8-[3-(3,4-dimethoxy-phenyl)-propyl]-9-...)
Affinity DataIC50:  229nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50106027((7S,8R,11S)-8-[3-(3,4-dimethoxy-phenyl)-propyl]-9-...)
Affinity DataIC50:  230nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed