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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Interstitial collagenase
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50071264
((9S,10R,13S)-10-Isobutyl-11-oxo-2-oxa-12-aza-bicyc...)
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Affinity Data
IC50: 2.20nM
Assay Description:
Inhibition of fibroblast collagenase (MMP-1)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Matrilysin
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50071264
((9S,10R,13S)-10-Isobutyl-11-oxo-2-oxa-12-aza-bicyc...)
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Affinity Data
IC50: 5.70nM
Assay Description:
Inhibition of fibroblast matrilysin (MMP-7)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50071264
((9S,10R,13S)-10-Isobutyl-11-oxo-2-oxa-12-aza-bicyc...)
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Affinity Data
IC50: 5.90nM
Assay Description:
Inhibition of fibroblast gelatinase A (MMP-2)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50071264
((9S,10R,13S)-10-Isobutyl-11-oxo-2-oxa-12-aza-bicyc...)
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Copy InChI
Affinity Data
IC50: 12nM
Assay Description:
Inhibition of fibroblast stromelysin (MMP-3)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI