Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 13 hits in this display   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183845((R)-1-((4-(3-chloro-2-fluorophenylamino)-7-methoxy...)
Affinity DataIC50:  50nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183845((R)-1-((4-(3-chloro-2-fluorophenylamino)-7-methoxy...)
Affinity DataIC50:  50nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183845((R)-1-((4-(3-chloro-2-fluorophenylamino)-7-methoxy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183845((R)-1-((4-(3-chloro-2-fluorophenylamino)-7-methoxy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183845((R)-1-((4-(3-chloro-2-fluorophenylamino)-7-methoxy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of SAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183845((R)-1-((4-(3-chloro-2-fluorophenylamino)-7-methoxy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PKAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183845((R)-1-((4-(3-chloro-2-fluorophenylamino)-7-methoxy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183845((R)-1-((4-(3-chloro-2-fluorophenylamino)-7-methoxy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183845((R)-1-((4-(3-chloro-2-fluorophenylamino)-7-methoxy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183845((R)-1-((4-(3-chloro-2-fluorophenylamino)-7-methoxy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of SGKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183845((R)-1-((4-(3-chloro-2-fluorophenylamino)-7-methoxy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10/8/9(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183845((R)-1-((4-(3-chloro-2-fluorophenylamino)-7-methoxy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183845((R)-1-((4-(3-chloro-2-fluorophenylamino)-7-methoxy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MAPKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed