Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215763(1-methyl-3-(5-((1-methyl-4-((4-(trifluoromethylthi...)
Affinity DataIC50:  15nMAssay Description:Inhibition of pAktMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215763(1-methyl-3-(5-((1-methyl-4-((4-(trifluoromethylthi...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215763(1-methyl-3-(5-((1-methyl-4-((4-(trifluoromethylthi...)
Affinity DataIC50:  62nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215763(1-methyl-3-(5-((1-methyl-4-((4-(trifluoromethylthi...)
Affinity DataIC50:  154nMAssay Description:Inhibition of b-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215763(1-methyl-3-(5-((1-methyl-4-((4-(trifluoromethylthi...)
Affinity DataIC50:  899nMAssay Description:Inhibition of P-ERKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed