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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human))
Novartis
Ligand
BDBM26026
(N-methyl-4-[(2-{methyl[4-(trifluoromethyl)phenyl]a...)
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Affinity Data
IC50: 9nM
pH: 7.8 T: 2°C
Assay Description:
To measure compound inhibitor effects on the ability of Raf enzymes to phosphorylate the Mek substrate, a capture ELISA utilizing streptavidin-coated...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Serine/threonine-protein kinase B-raf [V600E]
(Homo sapiens (Human))
Novartis
Ligand
BDBM26026
(N-methyl-4-[(2-{methyl[4-(trifluoromethyl)phenyl]a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 88nM
Assay Description:
To measure compound inhibitor effects on the ability of Raf enzymes to phosphorylate the Mek substrate, a capture ELISA utilizing streptavidin-coated...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI