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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150831(4-[(N-Cyclohexyl-3-methylamino-pyrrolidine-1-carbo...)
Affinity DataKi:  36nMAssay Description:Inhibition of [125I]-NDP-MSH binding to human Melanocortin 5 receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150831(4-[(N-Cyclohexyl-3-methylamino-pyrrolidine-1-carbo...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity for human melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150831(4-[(N-Cyclohexyl-3-methylamino-pyrrolidine-1-carbo...)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity for human melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150831(4-[(N-Cyclohexyl-3-methylamino-pyrrolidine-1-carbo...)
Affinity DataIC50:  630nMAssay Description:Inhibition of human Melanocortin 5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150831(4-[(N-Cyclohexyl-3-methylamino-pyrrolidine-1-carbo...)
Affinity DataEC50:  4.60E+3nMAssay Description:Agonistic activity for human Melanocortin 4 receptor as stimulated cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed