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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
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Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Sumitomo Dainippon Pharma
US Patent
Ligand
BDBM322089
(1-{5-[(2,5-difluorobenzyl)oxy]-1-(4-methylbenzyl)-...)
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Affinity Data
Ki: 2.30nM
Assay Description:
The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Sumitomo Dainippon Pharma
US Patent
Ligand
BDBM322089
(1-{5-[(2,5-difluorobenzyl)oxy]-1-(4-methylbenzyl)-...)
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Copy InChI
Affinity Data
Ki: 2.30nM
Assay Description:
The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Sumitomo Dainippon Pharma
US Patent
Ligand
BDBM322089
(1-{5-[(2,5-difluorobenzyl)oxy]-1-(4-methylbenzyl)-...)
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Copy InChI
Affinity Data
Ki: 2.30nM
Assay Description:
Specifically, a solution containing 50 μL of [3H]-citalopram (GE Healthcare) diluted with SERT buffer (50 mmol/L Tris-HCl (pH=7.4) containing 12...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
Sumitomo Pharma
US Patent
Ligand
BDBM322089
(1-{5-[(2,5-difluorobenzyl)oxy]-1-(4-methylbenzyl)-...)
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Affinity Data
Ki: 2.70nM
Assay Description:
5-HT2A: A solution containing 50 μL of [H]-ketanserin (the final concentration: 1 nM), 2 μL of a solution of a test compound in DMSO or a s...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Homo sapiens)
Sumitomo Pharma
US Patent
Ligand
BDBM322089
(1-{5-[(2,5-difluorobenzyl)oxy]-1-(4-methylbenzyl)-...)
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Affinity Data
Ki: 4.90nM
Assay Description:
5-HT2C: A solution containing 50 μL of [H]-mesulergine (GE Healthcare) diluted with 50 mmol/L Tris-HCl (pH=7.4) (the final concentration: about ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
Sumitomo Dainippon Pharma
US Patent
Ligand
BDBM322089
(1-{5-[(2,5-difluorobenzyl)oxy]-1-(4-methylbenzyl)-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.90nM
Assay Description:
A solution of 200 μL in total was prepared by mixing 50 μL of [3H] mesulergine (manufactured by GE Healthcare) diluted with 50 mmol/L Tris-...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
Sumitomo Dainippon Pharma
US Patent
Ligand
BDBM322089
(1-{5-[(2,5-difluorobenzyl)oxy]-1-(4-methylbenzyl)-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.90nM
Assay Description:
A solution of 200 μL in total was prepared by mixing 50 μL of [3H] mesulergine (manufactured by GE Healthcare) diluted with 50 mmol/L Tris-...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI