Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL

LigandBDBM50428709(CHEMBL2333135 | US9884828, 2-94)Copy SMILESCopy InChI

Affinity DataIC50:  119nMAssay Description:Inhibition of wild type GST-tagged LRRK2 (970 to 2527 amino acid residues) (unknown origin) assessed as inhibition of biotinylated-LRRKtide phosphory...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL

LigandBDBM50428709(CHEMBL2333135 | US9884828, 2-94)Copy SMILESCopy InChI

Affinity DataIC50:  120nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI