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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50301542
(4-fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4...)
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Affinity Data
Ki: 7.90E+3nM
Assay Description:
Binding affinity to human mGluR5 by PDSP assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
D(2) dopamine receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50301542
(4-fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to human dopamine D2 receptor by PDSP assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50301542
(4-fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to human sigma-1 receptor by PDSP assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Histamine H1 receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50301542
(4-fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4...)
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Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to human histamine H1 receptor by PDSP assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Translocator protein
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50301542
(4-fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to human TSPO receptor by PDSP assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50301542
(4-fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to human 5-HT3 receptor by PDSP assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 1
(Homo sapiens (Human))
Tsukuba Research Institute
Curated by
ChEMBL
Ligand
BDBM50301542
(4-fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4...)
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Copy InChI
Affinity Data
IC50: 1.80nM
Assay Description:
Antagonist activity at human mGluR1 receptor expressed in CHO cells by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50301542
(4-fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.90E+3nM
Assay Description:
Antagonist activity at human mGluR5 receptor expressed in CHO cells by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI