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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetS-adenosylmethionine synthase(Escherichia coli)
University of Kentucky

LigandPNGBDBM102425(FIDAS-5 | Fluorinated N,N-Dialkylaminostilbenes 5)
Affinity DataIC50:  2.10E+3nMAssay Description:MAT2A was incubated with FIDAS agents at RT for 20 min andthen mixed with L-methionine and ATP in 0.5 mL of reaction buffer.Cold deionized water (2 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM102425(FIDAS-5 | Fluorinated N,N-Dialkylaminostilbenes 5)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human recombinant His-tagged MAT2A expressed in Escherichia coli expression system assessed as S-adenosyl methionine production using L...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM102425(FIDAS-5 | Fluorinated N,N-Dialkylaminostilbenes 5)
Affinity DataIC50:  4.98E+4nMAssay Description:Inhibition of human ERG over-expressed in HEK293 cell membrane by [3H]dofetilide binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed