Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50426395(CHEMBL2326713)Copy SMILESCopy InChI

Affinity DataIC50:  52nMAssay Description:Inhibition of LRRK2 (unknown origin) autophosphorylation by cell-based assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 1A2(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50426395(CHEMBL2326713)Copy SMILESCopy InChI

Affinity DataIC50:  700nMAssay Description:Reversible inhibition of CYP1A2 (unknown origin) using phenacetin as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI