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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Thromboxane-A synthase
(Homo sapiens (Human))
Eisai
Curated by
ChEMBL
Ligand
BDBM50037037
(5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...)
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Affinity Data
IC50: 9nM
Assay Description:
Tested for inhibitory activity against thromboxane A2 (TXA2) synthetase in microsome of human platelets
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thromboxane-A synthase
(Homo sapiens (Human))
Eisai
Curated by
ChEMBL
Ligand
BDBM50037037
(5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 90nM
Assay Description:
Inhibitory concentration against thromboxane A2 synthase
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thromboxane-A synthase
(Rattus norvegicus)
Eisai
Curated by
ChEMBL
Ligand
BDBM50037037
(5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 90nM
Assay Description:
Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of rat
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Organon Laboratories
Curated by
ChEMBL
Ligand
BDBM50037037
(5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...)
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Copy InChI
Affinity Data
IC50: 100nM
Assay Description:
Inhibition constant against arachidonate 5-lipoxygenase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus)
Eisai
Curated by
ChEMBL
Ligand
BDBM50037037
(5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 100nM
Assay Description:
Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of rat
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Leukotriene B4 receptor 1
(Homo sapiens (Human))
Eisai
Curated by
ChEMBL
Ligand
BDBM50037037
(5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 210nM
Assay Description:
Tested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophils
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus)
Eisai
Curated by
ChEMBL
Ligand
BDBM50037037
(5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 230nM
Assay Description:
Tested for inhibitory activity against 5-lipoxygenase in microsome of RBL-1 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI