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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194669
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
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Affinity Data
IC50: 48nM
Assay Description:
Inhibition of Lck by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194669
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
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Copy InChI
Affinity Data
IC50: 168nM
Assay Description:
Inhibition of p38-alpha by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase JAK3
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194669
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
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Copy InChI
Affinity Data
IC50: 253nM
Assay Description:
Inhibition of Jak3 by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194669
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.42E+3nM
Assay Description:
Inhibition of KDR by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI