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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Chemical Diversity Research Institute
Curated by
ChEMBL
Ligand
BDBM103504
(CHEMBL2172192 | US8552017, 2(7).HCl)
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Affinity Data
Ki: 0.820nM
Assay Description:
Displacement of [3H]lysergic acid diethylamide from human recombinant 5HT6 receptor expressed in HeLa cells after 120 mins
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Target Info
PDB
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KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
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CHEMBL
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PubMed
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Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Chemical Diversity Research Institute
Curated by
ChEMBL
Ligand
BDBM103504
(CHEMBL2172192 | US8552017, 2(7).HCl)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.26nM IC50: 7.02nM
Assay Description:
The screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out b the method of radio...
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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In Depth
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US Patent
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Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Chemical Diversity Research Institute
Curated by
ChEMBL
Ligand
BDBM103504
(CHEMBL2172192 | US8552017, 2(7).HCl)
Copy SMILES
Copy InChI
Affinity Data
Ki: 14.3nM
Assay Description:
Antagonist activity at human recombinant 5HT6 receptor expressed in HE293 cells assessed as inhibition of serotonin-induced cAMP accumulation after 2...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Chemical Diversity Research Institute
Curated by
ChEMBL
Ligand
BDBM103504
(CHEMBL2172192 | US8552017, 2(7).HCl)
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Affinity Data
IC50: 500nM
Assay Description:
Inhibition of human recombinant ERG channel expressed in HEK297 cells after 3 to 8 mins by voltage clamp assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI