Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL

LigandBDBM50176723((R)-3-(3-methoxyquinuclidin-3-yl)-1,1-di(thiophen-...)Copy SMILESCopy InChI

Affinity DataKi:  0.0500nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
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TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL

LigandBDBM50176723((R)-3-(3-methoxyquinuclidin-3-yl)-1,1-di(thiophen-...)Copy SMILESCopy InChI

Affinity DataKi:  0.200nMAssay Description:Binding affinity to human muscarinic M2 receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMuscarinic acetylcholine receptor(Cavia porcellus)
Ucb Pharma

Curated by ChEMBL

LigandBDBM50176723((R)-3-(3-methoxyquinuclidin-3-yl)-1,1-di(thiophen-...)Copy SMILESCopy InChI

Affinity DataKd:  2.5nMAssay Description:Antagonism in muscarinic M3 receptor in guinea pig left atriaMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/TrEMBL
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI