Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM103293(US8546404, 480)Copy SMILESCopy InChI

Affinity DataIC50:  4.80nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
Merck Sharp & Dohme

US Patent

LigandBDBM103293(US8546404, 480)Copy SMILESCopy InChI

Affinity DataIC50:  4.80nMAssay Description:Activated ERK2 activity was determined in the IMAP assay format.More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI