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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Mu-type opioid receptor
(Homo sapiens (Human))
University Of Bristol
Curated by
ChEMBL
Ligand
BDBM50084276
(7,7-Spiro analogue ofBuprinorphine | CHEMBL416765)
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Affinity Data
Ki: 0.260nM
Assay Description:
Binding affinity to cloned human Opioid receptor mu 1 transfected into hamster ovary cells using [3H]DAMGO as a radioligand.
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Homo sapiens (Human))
University Of Bristol
Curated by
ChEMBL
Ligand
BDBM50084276
(7,7-Spiro analogue ofBuprinorphine | CHEMBL416765)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.870nM
Assay Description:
Binding affinity to cloned human Opioid receptor kappa 1 transfected into hamster ovary cells using [3H]U-69593 as a radioligand.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Homo sapiens (Human))
University Of Bristol
Curated by
ChEMBL
Ligand
BDBM50084276
(7,7-Spiro analogue ofBuprinorphine | CHEMBL416765)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.5nM
Assay Description:
Binding affinity to cloned human Opioid receptor delta 1 transfected into hamster ovary cells using [3H]DPDPE as a radioligand.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Homo sapiens (Human))
University Of Bristol
Curated by
ChEMBL
Ligand
BDBM50084276
(7,7-Spiro analogue ofBuprinorphine | CHEMBL416765)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6.10nM
Assay Description:
GTPgammaS binding in cloned human Opioid receptor delta 1 transfected into hamster ovary cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Homo sapiens (Human))
University Of Bristol
Curated by
ChEMBL
Ligand
BDBM50084276
(7,7-Spiro analogue ofBuprinorphine | CHEMBL416765)
Copy SMILES
Copy InChI
Affinity Data
EC50: 11nM
Assay Description:
GTPgammaS binding in cloned human Opioid receptor kappa 1 transfected into hamster ovary cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Homo sapiens (Human))
University Of Bristol
Curated by
ChEMBL
Ligand
BDBM50084276
(7,7-Spiro analogue ofBuprinorphine | CHEMBL416765)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.70nM
Assay Description:
GTPgammaS binding in cloned human Opioid receptor mu 1 transfected into hamster ovary cells
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI