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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

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TargetBeta-secretase 1 [1-454](Homo sapiens (Human))
Vitae Pharmaceutical

US Patent
LigandPNGBDBM259487(US9526727, Comparison Example Table 2, (1r,1'R,4R)...)
Affinity DataIC50:  415nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent