Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 10 hits in this display
BDBM155100(US9000182, 9, isomer 1)
BDBM155100(US9000182, 9, isomer 1)
IC50: 1.60nMT: 2°CAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at -140 C. at a concent...More data for this Ligand-Target Pair
BDBM136880(US10231967, Example 113 | US8865911, 113 | US90001...)
IC50: 4.70nMpH: 2.5Assay Description:TR-FRET Assay: The beta -secretase enzyme used in the TR-FRET is prepared as follows:The cDNA for the soluble part of the human (3-Secretase (AA 1-AA...More data for this Ligand-Target Pair
BDBM136880(US10231967, Example 113 | US8865911, 113 | US90001...)
BDBM136880(US10231967, Example 113 | US8865911, 113 | US90001...)
BDBM136880(US10231967, Example 113 | US8865911, 113 | US90001...)
BDBM136880(US10231967, Example 113 | US8865911, 113 | US90001...)
IC50: 678nMT: 2°CAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at -140 C. at a concent...More data for this Ligand-Target Pair
BDBM136880(US10231967, Example 113 | US8865911, 113 | US90001...)