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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Beta-secretase 1
(Homo sapiens (Human))
Vitae Pharmaceuticals
US Patent
Ligand
BDBM113329
(US10336717, Compound 497 | US8633212, 497 | US9212...)
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Copy InChI
Affinity Data
IC50: 144nM
Assay Description:
For each compound being tested, the BACE activity was monitored in a fluorescence quenching assay (FRET) using the ectodomain of BACE (aa 1-454) fuse...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Isoform C of Beta-secretase 1 (BACE-I-457)
(Homo sapiens (Human))
Vitae Pharmaceuticals
US Patent
Ligand
BDBM113329
(US10336717, Compound 497 | US8633212, 497 | US9212...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 144nM
Assay Description:
For each compound being tested, the BACE activity was monitored in a fluorescence quenching assay (FRET) using the ectodomain of BACE (aa 1-454) fuse...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Beta-secretase 1 [1-458]
(Homo sapiens (Human))
Vitae Pharmaceuticals
US Patent
Ligand
BDBM113329
(US10336717, Compound 497 | US8633212, 497 | US9212...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 144nM
pH: 4.4
Assay Description:
For each compound being tested, the BACE activity was monitored in a fluorescence quenching assay (FRET) using the ectodomain of BACE (aa 1-454) fuse...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI