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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
14
hits in this display
Target
Serine/threonine-protein kinase mTOR
(Homo sapiens (Human))
Celgene
Curated by
ChEMBL
Ligand
BDBM50092783
(CHEMBL3586404)
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Affinity Data
IC50: 10nM
Assay Description:
Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Target
Serine/threonine-protein kinase mTOR
(Homo sapiens (Human))
Celgene
Curated by
ChEMBL
Ligand
BDBM50092783
(CHEMBL3586404)
Copy SMILES
Copy InChI
Affinity Data
IC50: 16nM
Assay Description:
Inhibition of mTOR (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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CHEMBL
MCE
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Article
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Target
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human))
Celgene
Curated by
ChEMBL
Ligand
BDBM50092783
(CHEMBL3586404)
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Affinity Data
IC50: 28nM
Assay Description:
Inhibition of cFMS (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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Target
FKBP12A/mTOR
(Homo sapiens (Human))
Celgene
Curated by
ChEMBL
Ligand
BDBM50092783
(CHEMBL3586404)
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Affinity Data
IC50: 30nM
Assay Description:
Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hr
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
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Target
Vascular endothelial growth factor receptor 3
(Homo sapiens (Human))
Celgene
Curated by
ChEMBL
Ligand
BDBM50092783
(CHEMBL3586404)
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Affinity Data
IC50: 651nM
Assay Description:
Inhibition of Flt4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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antibodypedia
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Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Celgene
Curated by
ChEMBL
Ligand
BDBM50092783
(CHEMBL3586404)
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Copy InChI
Affinity Data
IC50: 4.00E+3nM
Assay Description:
Inhibition of PI3K-alpha (unknown origin) by mobility shift assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Celgene
Curated by
ChEMBL
Ligand
BDBM50092783
(CHEMBL3586404)
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Affinity Data
IC50: 3.30E+4nM
Assay Description:
Inhibition of human ERG
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human))
University Of Basel
Curated by
ChEMBL
Ligand
BDBM50092783
(CHEMBL3586404)
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Affinity Data
Kd: 6.20E+3nM
Assay Description:
Inhibition of human PI3Kdelta (108 to 1044 residues) expressed in mammalian expression system by KINOMEscan assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
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Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human))
University Of Basel
Curated by
ChEMBL
Ligand
BDBM50092783
(CHEMBL3586404)
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Affinity Data
Kd: 1.80E+4nM
Assay Description:
Inhibition of human PI3Kbeta (118 to 1070 residues) expressed in mammalian expression system by KINOMEscan assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
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B.MOAD
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antibodypedia
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CHEMBL
MCE
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In Depth
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Article
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Target
Phosphatidylinositol 3-kinase catalytic subunit type 3
(Homo sapiens (Human))
University Of Basel
Curated by
ChEMBL
Ligand
BDBM50092783
(CHEMBL3586404)
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Affinity Data
Kd: 2.50E+3nM
Assay Description:
Inhibition of human VPS34 (282 to 879 residues) expressed in mammalian expression system by KINOMEscan assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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Target
Phosphatidylinositol 4-kinase beta
(Homo sapiens (Human))
University Of Basel
Curated by
ChEMBL
Ligand
BDBM50092783
(CHEMBL3586404)
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Affinity Data
Kd: 39nM
Assay Description:
Inhibition of human PI4Kbeta (1 to 828 residues) expressed in mammalian expression system by KINOMEscan assay
More data for this Ligand-Target Pair
Target Info
PDB
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CHEMBL
MCE
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Article
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Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human))
University Of Basel
Curated by
ChEMBL
Ligand
BDBM50092783
(CHEMBL3586404)
Copy SMILES
Copy InChI
Affinity Data
Kd: 7.10E+3nM
Assay Description:
Inhibition of human PI3Kgamma (144 to 1102 residues) expressed in mammalian expression system by KINOMEscan assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Celgene
Curated by
ChEMBL
Ligand
BDBM50092783
(CHEMBL3586404)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.30E+3nM
Assay Description:
Inhibition of human PI3Kalpha (108 to 1068 residues) expressed in mammalian expression system by KINOMEscan assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase mTOR
(Homo sapiens (Human))
Celgene
Curated by
ChEMBL
Ligand
BDBM50092783
(CHEMBL3586404)
Copy SMILES
Copy InChI
Affinity Data
Kd: 28nM
Assay Description:
Inhibition of human mTOR (1382 to 2549 residues) expressed in mammalian expression system by KINOMEscan assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI