Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 5 hits in this display
BDBM155140(US9000184, 10, isomer 1)
BDBM155140(US9000184, 10, isomer 1)
BDBM155141(US9000184, 10, isomer 2)
IC50: 92nMT: 2°CAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at -140 C. at a concent...More data for this Ligand-Target Pair
BDBM155141(US9000184, 10, isomer 2)
BDBM155143(US9000184, 11, isomer 2)
IC50: >5.00E+3nMpH: 2.5Assay Description:The beta -secretase enzyme used in the TR-FRET is prepared as follows:The cDNA for the soluble part of the human beta -Secretase (AA 1-AA 460) was cl...More data for this Ligand-Target Pair