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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
16
hits in this display
Target
Muscarinic acetylcholine receptor M2
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50061705
((R)-1-Aza-bicyclo[2.2.2]oct-3-yl-[(Z)-methoxyimino...)
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Affinity Data
Ki: 204nM
Assay Description:
Binding affinity to human cloned muscarinic M2 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
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Target
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50061705
((R)-1-Aza-bicyclo[2.2.2]oct-3-yl-[(Z)-methoxyimino...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 229nM
Assay Description:
Binding affinity to human cloned muscarinic M1 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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Target
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5
(RAT)
TBA
Ligand
BDBM50212570
(BRL-55473 | CHEMBL336590)
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Affinity Data
IC50: 33nM
Assay Description:
In vitro binding affinity against Muscarinic receptor in rat cerebral cortex using [3H]- oxotremorine-M (OXO-M) using as a radioligand; Value ranges ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
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In Depth
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Article
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5
(RAT)
TBA
Ligand
BDBM50212570
(BRL-55473 | CHEMBL336590)
Copy SMILES
Copy InChI
Affinity Data
IC50: 33nM
Assay Description:
In vitro inhibition of oxotremorine-M (OXO-M) binding to muscarinic receptors of rat cerebral cortex
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50061705
((R)-1-Aza-bicyclo[2.2.2]oct-3-yl-[(Z)-methoxyimino...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 60nM
Assay Description:
In vitro affinity of the compound is evaluated, using quinuclidynyl benzylate (QNB) as radioligand in human cloned Muscarinic acetylcholine receptor ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M4
(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50061705
((R)-1-Aza-bicyclo[2.2.2]oct-3-yl-[(Z)-methoxyimino...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 90nM
Assay Description:
In vitro affinity of the compound is evaluated, using quinuclidynyl benzylate (QNB) as radioligand in human cloned Muscarinic acetylcholine receptor ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50061705
((R)-1-Aza-bicyclo[2.2.2]oct-3-yl-[(Z)-methoxyimino...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 170nM
Assay Description:
In vitro affinity against human Muscarinic acetylcholine receptor M1 using quinuclidynyl benzylate (QNB)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M2
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50061705
((R)-1-Aza-bicyclo[2.2.2]oct-3-yl-[(Z)-methoxyimino...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 180nM
Assay Description:
In vitro affinity of the compound is evaluated, using quinuclidynyl benzylate (QNB) as radioligand in human cloned Muscarinic acetylcholine receptor ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5
(RAT)
TBA
Ligand
BDBM50212570
(BRL-55473 | CHEMBL336590)
Copy SMILES
Copy InChI
Affinity Data
IC50: 470nM
Assay Description:
In vitro inhibition of [3H]quinuclidinyl benzilate (QNB) binding to muscarinic receptors of rat cerebral cortex
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5
(RAT)
TBA
Ligand
BDBM50212570
(BRL-55473 | CHEMBL336590)
Copy SMILES
Copy InChI
Affinity Data
IC50: 470nM
Assay Description:
In vitro binding affinity against Muscarinic receptor in rat cerebral cortex using [3H]- quinuclidinyl benzilate (QNB)using as a radioligand; Value r...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50061705
((R)-1-Aza-bicyclo[2.2.2]oct-3-yl-[(Z)-methoxyimino...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 64nM
Assay Description:
Agonist activity at human muscarinic M1 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M4
(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50061705
((R)-1-Aza-bicyclo[2.2.2]oct-3-yl-[(Z)-methoxyimino...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 214nM
Assay Description:
Agonist activity at human muscarinic M4 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M2
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50061705
((R)-1-Aza-bicyclo[2.2.2]oct-3-yl-[(Z)-methoxyimino...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 62nM
Assay Description:
Agonist activity at human muscarinic M2 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50061705
((R)-1-Aza-bicyclo[2.2.2]oct-3-yl-[(Z)-methoxyimino...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 117nM
Assay Description:
Agonist activity at human muscarinic M3 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M4
(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50061705
((R)-1-Aza-bicyclo[2.2.2]oct-3-yl-[(Z)-methoxyimino...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 5.70nM
Assay Description:
Partial agonist activity at human M4 receptor co-expressed with Galpha16 in CHO cells assessed as calcium mobilization after 60 mins by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M5
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50061705
((R)-1-Aza-bicyclo[2.2.2]oct-3-yl-[(Z)-methoxyimino...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 123nM
Assay Description:
Agonist activity at human muscarinic M5 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI