Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL

LigandBDBM50082799(4-(4-Fluoro-phenyl)-3-[3-(4-methoxycarbonyl-4-phen...)Copy SMILESCopy InChI

Affinity DataKi:  1.20nMAssay Description:In vitro binding affinity against Alpha-1A adrenergic receptor of human liver microsomes.More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL

LigandBDBM50082799(4-(4-Fluoro-phenyl)-3-[3-(4-methoxycarbonyl-4-phen...)Copy SMILESCopy InChI

Affinity DataKi:  78nMAssay Description:In vitro binding affinity against Alpha-1B adrenergic receptor of human liver microsomes.More data for this Ligand-Target Pair

Target InfoReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL

LigandBDBM50082799(4-(4-Fluoro-phenyl)-3-[3-(4-methoxycarbonyl-4-phen...)Copy SMILESCopy InChI

Affinity DataKi:  180nMAssay Description:In vitro binding affinity against Alpha-1D adrenergic receptor of human liver microsomes.More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI