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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
26
hits in this display
Target
Transporter
(Rattus norvegicus)
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50046737
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
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Affinity Data
Ki: 5.90nM
Assay Description:
Inhibition of 0.5 nM [3H]nisoxetine binding to Norepinephrine transporter
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Transporter
(Rattus norvegicus)
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50046737
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.90nM
Assay Description:
Inhibition of 0.2 nM [3H]paroxetine binding to Serotonin transporter
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50046737
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.24nM
Assay Description:
Displacement of [3H]paroxetine from serotonin transporter (5-HT) of rat cerebral cortex
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50046737
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.24nM
Assay Description:
Displacement of [3H]paroxetine from serotonin transporter (5-HT) of rat cerebral cortex
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50046737
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 8.40nM
Assay Description:
Inhibition of 0.2 nM [3H]paroxetine binding to Serotonin transporter
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50046737
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 8.40nM
Assay Description:
Inhibition of 0.2 nM [3H]paroxetine binding to Serotonin transporter
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Transporter
(Rattus norvegicus)
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50046737
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 11.3nM
Assay Description:
Displacement of [3H]nisoxetine from norepinephrine transporter (NET) of rat cerebral cortex
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Transporter
(Rattus norvegicus)
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50046737
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 11.3nM
Assay Description:
Displacement of [3H]nisoxetine from norepinephrine transporter (NET) of rat cerebral cortex
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50046737
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.40nM
Assay Description:
Inhibition of [3H]WIN-35428 binding to rat striatal dopamine transporter
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50012154
((3S,8R)-3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]oc...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.40nM
Assay Description:
Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporter
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50046737
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.40nM
Assay Description:
Inhibition of [3H]WIN-35428 binding to rat striatal dopamine transporter
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Transporter
(Rattus norvegicus)
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50046737
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.80nM
Assay Description:
Inhibition of 0.2 nM [3H]paroxetine binding to Serotonin transporter
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Transporter
(Rattus norvegicus)
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50046737
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.80nM
Assay Description:
Inhibition of 0.5 nM [3H]nisoxetine binding to Norepinephrine transporter
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Transporter
(Rattus norvegicus)
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50046737
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 18.8nM
Assay Description:
Inhibition of [3H]nisoxetine binding to rat cerebral cortex norepinephrine transporter
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Transporter
(Rattus norvegicus)
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50046737
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 18.8nM
Assay Description:
Inhibition of [3H]nisoxetine binding to rat cerebral cortex norepinephrine transporter
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Transporter
(Rattus norvegicus)
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50012154
((3S,8R)-3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]oc...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 19nM
Assay Description:
Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporter
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50046737
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 32.6nM
Assay Description:
Displacement of 0.5 nM [3H]WIN-35248 from Dopamine transporter
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50046737
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 33nM
Assay Description:
Displacement of 0.5 nM [3H]WIN-35248 from Dopamine transporter
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Organix
Curated by
ChEMBL
Ligand
BDBM50046737
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 34nM
Assay Description:
Inhibition of [3H]3-beta-(4-fluorophenyl)tropane-2beta-carboxylic acid methyl ester binding to dopamine transporter of cynomolgus monkey striatum
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50005573
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 36nM
Assay Description:
Inhibition of [3H]cocaine binding to the dopamine transporter.
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50012154
((3S,8R)-3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]oc...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 36nM
Assay Description:
Compound was evaluated for inhibition of specifically bound [3H]- cocaine (2.7 nM) against Dopamine transporter in cynomolgus monkeys
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50046737
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 68.6nM
Assay Description:
Inhibition of [3H]paroxetine binding to rat cortex serotonin transporter
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50046737
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 68.6nM
Assay Description:
Inhibition of [3H]paroxetine binding to rat cortex serotonin transporter
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50012154
((3S,8R)-3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]oc...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 69nM
Assay Description:
Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporter
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50046737
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 92nM
Assay Description:
Inhibition of 0.2 nM [3H]paroxetine binding to Serotonin transporter
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50046737
(3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 92.4nM
Assay Description:
Inhibition of 0.2 nM [3H]paroxetine binding to Serotonin transporter
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI