Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 7 hits in this display
BDBM236788(US9388149, 19 | US9580412, Example 19)
BDBM236788(US9388149, 19 | US9580412, Example 19)
IC50: 11nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
BDBM236788(US9388149, 19 | US9580412, Example 19)
BDBM236788(US9388149, 19 | US9580412, Example 19)
IC50: 20nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
BDBM236788(US9388149, 19 | US9580412, Example 19)
IC50: 42nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
BDBM236788(US9388149, 19 | US9580412, Example 19)
IC50: 42nMT: 2°CAssay Description:PathHunter HEK293-CXCR2 or U2OS hCXCR1 β-arrestin cells (DiscoveRx Corporation) were seeded overnight at 10 000 cells/well (384-well...More data for this Ligand-Target Pair
BDBM236788(US9388149, 19 | US9580412, Example 19)
IC50: 510nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair