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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Nociceptin receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM50173254
(CHEMBL434944 | methyl 2-[1'-cyclooctylmethyl-2-oxo...)
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Affinity Data
IC50: 100nM
Assay Description:
Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Kappa-type opioid receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM50173254
(CHEMBL434944 | methyl 2-[1'-cyclooctylmethyl-2-oxo...)
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Copy InChI
Affinity Data
IC50: 640nM
Assay Description:
Binding affinity against human opioid receptor kappa 1 expressed in HEK293 cells using 3H-U69,593 radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM50173254
(CHEMBL434944 | methyl 2-[1'-cyclooctylmethyl-2-oxo...)
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Affinity Data
IC50: 3.55E+3nM
Assay Description:
Binding affinity against human opioid receptor mu 1 expressed in HEK293 cells using [3H]DAMGO radioligand
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM50173254
(CHEMBL434944 | methyl 2-[1'-cyclooctylmethyl-2-oxo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Binding affinity against human opioid receptor delta 1 expressed in HEK293 cells using [3H]DDPDE radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI