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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Acetyl-CoA carboxylase 2 [151-2458]
(Homo sapiens (Human))
Sanofi
US Patent
Ligand
BDBM97617
(CHEMBL1629723 | US8470841, 46)
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Affinity Data
IC50: 210nM
pH: 7.5 T: 2°C
Assay Description:
the enzymatic activity of ACC and its inhibition by test substances were determined by a luminometric assay.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
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In Depth
Details
US Patent
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Target
Acetyl-CoA carboxylase 2
(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by
ChEMBL
Ligand
BDBM97617
(CHEMBL1629723 | US8470841, 46)
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Affinity Data
IC50: 250nM
Assay Description:
Inhibition of N-terminal His-tagged human recombinant ACC2 expressed in high five insect cells by ATP consumption assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Acetyl-CoA carboxylase 1
(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by
ChEMBL
Ligand
BDBM97617
(CHEMBL1629723 | US8470841, 46)
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Copy InChI
Affinity Data
IC50: 1.20E+3nM
Assay Description:
Inhibition of N-terminal His-tagged human recombinant ACC1 expressed in high five insect cells by ATP consumption assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetyl-CoA carboxylase 1
(Rattus norvegicus (Rat))
Sanofi-Aventis Deutschland
Curated by
ChEMBL
Ligand
BDBM97617
(CHEMBL1629723 | US8470841, 46)
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Affinity Data
IC50: 2.90E+3nM
Assay Description:
Inhibition of N-terminal His-tagged rat recombinant ACC1 expressed in high five insect cells by ATP consumption assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI