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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
B1 bradykinin receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50184183
(3,3'-difluoro-4'-{[5-(4-pyridin-4-yl-piperazine-1-...)
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Affinity Data
Ki: 0.0450nM
Assay Description:
Binding affinity to human BK1 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
B1 bradykinin receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50184183
(3,3'-difluoro-4'-{[5-(4-pyridin-4-yl-piperazine-1-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.0450nM
Assay Description:
Antagonist activity at human bradykinin B1 receptor expressed in human HEK293 cells assessed as calcium flux by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
B1 bradykinin receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50184183
(3,3'-difluoro-4'-{[5-(4-pyridin-4-yl-piperazine-1-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.0500nM
Assay Description:
Binding affinity to human BK1 receptor E273 mutant
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
B1 bradykinin receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50184183
(3,3'-difluoro-4'-{[5-(4-pyridin-4-yl-piperazine-1-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.0800nM
Assay Description:
Binding affinity to human BK1 receptor D291 mutant
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
B1 bradykinin receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50184183
(3,3'-difluoro-4'-{[5-(4-pyridin-4-yl-piperazine-1-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.830nM
Assay Description:
Binding affinity to human BK1 receptor N298 mutant
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
B1 bradykinin receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50184183
(3,3'-difluoro-4'-{[5-(4-pyridin-4-yl-piperazine-1-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.12nM
Assay Description:
Binding affinity to human BK1 receptor Q295 mutant
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI