Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL

LigandBDBM50274098(5-((S)-2-{(3S,4S)-5-(3,5-Difluoro-phenoxy)-3-hydro...)Copy SMILESCopy InChI

Affinity DataKi:  1.95E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL

LigandBDBM50274098(5-((S)-2-{(3S,4S)-5-(3,5-Difluoro-phenoxy)-3-hydro...)Copy SMILESCopy InChI

Affinity DataIC50:  220nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI