Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetChymotrypsinogen A(Bos taurus (bovine))
Welfide

Curated by ChEMBL

LigandBDBM50098839(2-{2-[2-(5-Amino-6-oxo-2-pyridin-3-yl-6H-pyrimidin...)Copy SMILESCopy InChI

Affinity DataKi:  45.1nMAssay Description:Inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetChymase(Homo sapiens (Human))
Welfide

Curated by ChEMBL

LigandBDBM50098839(2-{2-[2-(5-Amino-6-oxo-2-pyridin-3-yl-6H-pyrimidin...)Copy SMILESCopy InChI

Affinity DataKi:  77.4nMAssay Description:inhibitory activity was evaluated against chymase from human heart.More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI