Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL

LigandBDBM50117503(CHEMBL3613621)Copy SMILESCopy InChI

Affinity DataIC50: <1nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLIM domain kinase 2(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL

LigandBDBM50117503(CHEMBL3613621)Copy SMILESCopy InChI

Affinity DataIC50:  2.80nMAssay Description:Inhibition of ROCK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL

LigandBDBM50117503(CHEMBL3613621)Copy SMILESCopy InChI

Affinity DataIC50:  5.70nMAssay Description:Inhibition of LIMK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLIM domain kinase 1(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL

LigandBDBM50117503(CHEMBL3613621)Copy SMILESCopy InChI

Affinity DataIC50:  20nMAssay Description:Inhibition of LIMK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI