Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

LigandPNGBDBM28337((1R,2S)-1-{[4-(4-chlorophenyl)benzene]({2-[4-(meth...)
Affinity DataIC50:  73nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Universitetet I Oslo

US Patent
LigandPNGBDBM28337((1R,2S)-1-{[4-(4-chlorophenyl)benzene]({2-[4-(meth...)
Affinity DataIC50:  73nMAssay Description:Protein concentrations were measured using the Micro BCA Protein Assay Kit (Pierce/Thermo Scientific, IL). Sample buffer was mixed with 5-25 μg ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Universitetet I Oslo

US Patent
LigandPNGBDBM28337((1R,2S)-1-{[4-(4-chlorophenyl)benzene]({2-[4-(meth...)
Affinity DataIC50:  73nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed