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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1
(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft
US Patent
Ligand
BDBM162117
(US9682995, 32)
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Affinity Data
IC50: >2.00E+4nM
pH: 7.5 T: 2°C
Assay Description:
N-terminally His6-tagged recombinant catalytic domain of human Bub1 (amino acids 704-1085), expressed in insect cells (Hi5) and purified by Ni-NTA af...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Dual specificity protein kinase TTK
(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft
US Patent
Ligand
BDBM162117
(US9682995, 32)
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Affinity Data
IC50: >2.00E+4nM
pH: 7.7 T: 2°C
Assay Description:
N-terminally GST-tagged human full length recombinant Mps-1 kinase (purchased from Invitrogen, Karslruhe, Germany, cat. no PV4071) was used. As subst...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085]
(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft
US Patent
Ligand
BDBM162117
(US9682995, 32)
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Affinity Data
IC50: >2.00E+4nM
pH: 8.0
Assay Description:
Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI