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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
MAP kinase-interacting serine/threonine-protein kinase 2
(Homo sapiens (Human))
University Of South Australia
Curated by
ChEMBL
Ligand
BDBM98036
(US8486953, 19)
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Affinity Data
Ki: 4.05E+3nM
Assay Description:
Inhibition of human Mnk2a using TAMRA-labeled eIF4E peptide as substrate incubated for 10 mins followed by addition of ATP measured after 90 mins by ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human))
University Of South Australia
Curated by
ChEMBL
Ligand
BDBM98036
(US8486953, 19)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Inhibition of Mnk1a (unknown origin) using TAMRA-labeled eIF4E peptide as substrate incubated for 10 mins followed by addition of ATP measured after ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human))
University Of South Australia
Curated by
ChEMBL
Ligand
BDBM98036
(US8486953, 19)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Inhibition of CDK2/cyclinA (unknown origin) using TAMRA-labeled eIF4E peptide as substrate incubated for 10 mins followed by addition of ATP measured...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cyclin-T1/Cyclin-dependent kinase 9
(Homo sapiens (Human))
University Of South Australia
Curated by
ChEMBL
Ligand
BDBM98036
(US8486953, 19)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Inhibition of CDK9/cyclinT1 (unknown origin) using TAMRA-labeled eIF4E peptide as substrate incubated for 10 mins followed by addition of ATP measure...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
MAP kinase-interacting serine/threonine-protein kinase 2
(Homo sapiens (Human))
University Of South Australia
Curated by
ChEMBL
Ligand
BDBM98036
(US8486953, 19)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4nM
pH: 7.4 T: 2°C
Assay Description:
Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
MAP kinase-interacting serine/threonine-protein kinase 2
(Homo sapiens (Human))
University Of South Australia
Curated by
ChEMBL
Ligand
BDBM98036
(US8486953, 19)
Copy SMILES
Copy InChI
Affinity Data
IC50: 60nM
pH: 7.4
Assay Description:
In vitro kinase assay using human Mnk1 and Mnk2.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human))
University Of South Australia
Curated by
ChEMBL
Ligand
BDBM98036
(US8486953, 19)
Copy SMILES
Copy InChI
Affinity Data
IC50: 590nM
pH: 7.4
Assay Description:
In vitro kinase assay using human Mnk1 and Mnk2.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI